Our specialised trials registers

Access to the registers

The specialised registers are published in CENTRAL in the Cochrane Library. Cochrane contributors can also access the register via the Cochrane Register of Studies (CRS) Online. The registers can be searched by adding 'and SR-CF' to the end of your search strategy.


The editorial team developed and maintained databases of trials (“specialised registers”) as a resource for our review authors; and for all our reviews we undertook searches of the appropriate register – the Cystic Fibrosis Trials Register, the Haemoglobinopathies Trials Register, the Coagulopathy Trials Register or the Inborn Errors of Metabolism Trials Register. Each register was compiled from electronic searches of the Cochrane Central Register of Controlled Trials (CENTRAL) (updated each new issue of the Cochrane Library), weekly searches of MEDLINE and hand searching of journals and conferences relevant to each register.

We only included randomised controlled trials (RCTs) or quasi-RCTs (or those that could possibly be either) as defined by the Baltimore Cochrane Centre Hand Search Manual. They also needed to relate to one of the health conditions covered by the scope of the CFGD Group. Any trials identified were reviewed by the Information Specialist (IS) to ensure that they met the criteria for inclusion in our registers. All relevant references were then added to the appropriate specialised register. Some of our registers were “coded” with keywords for condition and intervention so it was possible to limit a search to a specific area of interest.

Note: Trials relating to haemophilia and HIV/AIDS were only included in the Coagulopathies Specialised Register if they assessed treatment of haemophilia. Those that look at HIV/AIDS treatment in individuals who also have haemophilia were not added to the register.